Tuberculosis: return with a vengeance
In an
Isolates from all patients were shipped to the tuberculosislaboratory at the US Centers for Disease Control and Prevention andtested for susceptibility to 11 antituberculosis drugs. Riskfactors for being infected with a strain resistant to second-linedrugs as well as for having extensively drug resistant (XDR)tuberculosis were assessed.
Worrying figures
The large, prospective study of resistance to second-line drugsfor multidrug-resistant tuberculosis shows comprehensively that theprevalence of resistance is high (43·7%), and that the risk ofextensive drug-resistant tuberculosis (6·7%) in the eight countriesstudied is worrying.
The researchers state that previous treatment with second-linedrugs is a strong, consistent risk factor for resistance to thesedrugs.
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